Let me put it like this. The ECU uses the MAF to determine how much fuel to add, because it know how much air is flowing in. Now it can do this because the MAF is giving it a nice reliable reading since the air is smoothly passing over the MAF sensors (those little resisters). Now if you remove the honeycomb, it can allow turbulent air to flow over the sensors, so it can get an unreliable reading.
Like the guy above posted, it may run alright, or it may not. Its totally up to you to decide if you want too.
If you want a gain you can install an LS1 MAF which are bigger but than you will need a tune to suit.