I'm not sure what you expect them to be able to do?
But there aren't any settings in the car which are saved & then change depending on the key-fob that's used. I think Calais (maybe only V - also Caprice) have that functionality though.
I think a few settings might change, my remote went flat last week so am using spare now. I always press lock button a few times, old key no horn sound, new key horn sound. Noticed when remote start. Also exit lighting changed.
Changed in mylink, personalisation or something - you'll find it.
One annoying thing that I found in going from VE to VF, (both Calais' V) was that newer car didn't adjust the drivers seat automatically between pressing unlock on the two different keyfobs like the VE did, instead you have to hold down the button on the drivers door. Not sure why they would have removed such a useful and convenient function.