Yes, what you will need to run them amplified is: a line out converter, set of 6x9 speakers, 2 channel amplifier (if these speakers are all you want amped), speaker wire and amp wiring kit. Wire up the amp the same way you usually would, but when you get to the RCAs, splice wires into the rear channel head unit outputs(run + to +, - to _ for both rear channels ect.) and run them into the line out converter which will have RCA outputs, then run your RCAs to your amp, and finally using speaker wire, connect the 6x9s in the parcel shelf to the amp.