There is a couple of things that come up straight away here!!
1, your gona make power and torque and a good wack of it I wouldn't so much worrie about 4 bolt mains but these days are using a main stud girdle contact pavtek these are around $300 but u need motor out or sump off to fit one then u need a ASR sump to fit over it !!!
2, when it comes to injector size really talk to ur tuner first sorry to say immortality but 60lbs will do much more the. 600 fwhp it comes down to fuel pressure and because it rises 60lbs will actually supply a lot more because pressure is up at 55 psi, at 43 psi yes 600hp but at around 55 psi they will do a lot more I'm make 500rwhp so some 640 fwhp now and am bearly pushing 70% duty cycle of 60lbs
3, what sort power are u after ??? I did all this research before I come onto this forum but I know lots of people have made more but after 550fwhp it is strongly advised to go to a forged crank exspecially with boost !!! A cast one will hold but for how long, and the torque these things make is strong and exspecially with 383 and a t trim blower the stroke is long with a lot of throw this 550 fwhp will come and go realy quick !!!
4, definetly change the cam as much lift as possible with 114 Lsa and u want more duration on exhaust side so if u pick something with 224 on the intake go about 232 or 234 on exhaust generally the second number should be about 8 or 10 bigger but with hydrolic and a aim of 6000rpm 114 Lsa is advised my revs more and is solid cam and pavtek advised me to go 112 as myn is a more reving race spec type of motor not so street friendly and doesn't hit boost till 3500rpm but this savage type of engine was what I was after dont do this if u drive it more then 1 a week u will regret it
5, use a felpro cometic head gasket !!! Myn is 0.040 thou thick !!!
6, 10.1 compression is high ( good for N/A) but I wouldn't recommend jamming boost down it and i u do dont go over about 6 psi !!! all this stuff comes down to how much u wana spend and how much power u want if u max that t trim every thing behind the crank and including the crank is gona cry help is it auto or manual and if manual 5 or 6 speed auto would need to be strong like fearly strong my mate had a t trim and chewed up and spat out 7 auto boxes the last cost him 6 grand and it held up but he abbused it hard, myn was 5 speed manual but there is no way it would hold up to this and t56 box is needed for manual way