For all intents and purposes the engine is just a big dumb lump of metal. If that lump of metal is so similar to another dumb lump of metal that it can be run by some other system within its parameters, then to that ECU it's not a different engine and should run correctly.
I'd throw the LFX in on the LLT ECU and see what happens. If it doesn't like it, swap the LLT heads and top end onto the LFX block, the blocks and displacement are the same and you'll get a bees dick of improvement in compression that would be well within the limits of the LLT ECUs knock control.